Celsus Laboratories

IMMOBILIZED GAGS

HEPARIN CARBOZONE® [AH-0357] is an affinity ligand and high capacity cation exchanger for the routine isolation of proteins. The heparin moiety in Heparin CarbozoneŽ has been structurally modified to introduce reactive aldehyde groups at the reducing end for end-point attachment with hydrazide groups on the beaded matrix to form hydrozone bonds. High dynamic capacity, low non-specific binding, and excellent pressure flow properties make Heparin CarbozoneŽ an exceptional choice for demanding, large scale purification of plasma proteins, restriction enzymes and other products.

References

Johnson PR, Stern NJ, Eitzman PD, Rasmussen JK, Milbraith DS, Gleason RM, Hogancamp RE. Reproducibility of physical characteristics, protein immobilization and chromatographic performance of 3M Emphaze Biosupport Medium AB 1. J Chromat 1994; A, 667: 1-9.
Smith PK, Mallia AK, Hermanson GT. Colorimetric Method for the Assay of Heparin Content in Immobilized Heparin Preparations. Anal Biochem 1980: 109: 466-473.

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